KBI Biopharma Acquires Alliance Protein Laboratories, Expands Biophysical Characterization Capabilities.
KBI Biopharma, Inc. (KBI) has agreed to acquire the assets of San Diego-based Alliance Protein Laboratories (Alliance), a leading analytical services company specializing in biophysical characterization of biopharmaceuticals. Founded in 1998, Alliance is well known and highly regarded around the world for its expertise in characterization of therapeutic proteins, peptides, nucleic acids and vaccines.
APL specializes in biophysical analysis of protein conformation, stability, and aggregation. We were the first contract lab in the US to offer analytical ultracentrifugation (AUC), and our principal scientists pioneered the application of biophysical techniques such as AUC, SEC-MALS, and circular dichroism (CD) in the biotechnology industry.
Alliance Protein Laboratories can provide research-scale protein purification services to generate microgram to gram quantities of proteins purified from either recombinant or natural sources. Our scientists have experience purifying and refolding scores of recombinant proteins from a variety of expression systems.
We do more than just proteins...
Our biophysical characterization techniques have applications to small peptides, nucleic acids (e.g. anti-sense therapeutics, aptamers, ribozymes), small molecule drugs, carbohydrates, vaccines, viruses, drug-polymer conjugates, and more.
APL offers contract research services in the areas of protein and peptide biophysical characterization, protein aggregation, protein purification, and protein stabilization.
If you are looking for analytical ultracentrifugation (AUC), circular dichroism, light scattering, DSC, fluorescence, or native gel analysis of your biotech product, or help with your protein aggregation problems, you have found the right place!
We have now done such analysis on literally hundreds of products, giving our scientists unparalleled experience.